Path of Exile 2: All Permanent Buffs in Act 4 and Interludes

Grinding Gear Games continues to refine the campaign progression in Path of Exile 2, and with Path of Exile 2 Currency Version 0.3 introducing The Third Edict, players now gain permanent upgrades through Act 4 and the Interludes instead of the old Cruel difficulty rewards. These permanent buffs are critical for both leveling and endgame prep, as they give you lasting bonuses to attributes, resistances, weapon set skill points, and more.

Whether you're pushing through the story for the first time or planning your next build for efficient progression, knowing where to get these permanent bonuses in PoE 2 Act 4 and the Interludes is essential. This guide breaks down every permanent buff, how to unlock them, and whether they're reversible.

Why Permanent Buffs Matter in Path of Exile 2

Permanent buffs are not temporary stat increases-they stay with your character throughout the campaign and into endgame content. They're essentially free power spikes that reward exploration, boss fights, and completing specific trials. Unlike gear upgrades that may be swapped out, these buffs become part of your character's foundation.

In Path of Exile 2, permanent buffs also offer flexibility: some are tied to attributes like Strength or Intelligence, while others enhance recovery or give skill points that directly expand your build options. Optimizing these choices is especially important if you're planning to min-max or compete in early mapping races. Players who buy POE2 Items often pair their gear investments with these permanent upgrades for maximum efficiency.

All Permanent Bonuses in Act 4

Act 4 introduces five different permanent buffs. Some require defeating bosses, while others come from activating shrines or statues. Here's the breakdown:

The Blind Beast - Isle of Kin

Reward: +2 Weapon Set Skill Points
How to Get: Defeat the Blind Beast.
Reversible: No.

This bonus is a direct DPS upgrade, as more weapon set skill points mean more room to customize your damage setup.

Navali's Rest - Eye of Hinekora - Silent Hall

Reward: +5% Increased Maximum Mana
How to Get: Activate the jade coffin in the Silent Hall.
Reversible: No.

Mana scaling buffs are especially useful for casters or mana-intensive builds like Totems.

Ancestral Tattoos - Halls of the Dead

Reward (choice of one):

+5 Dexterity or +5% Lightning Resistance
+5 Intelligence or +5% Cold Resistance
+5 Strength or +5% Fire Resistance

How to Get: Complete three trials in the map to unlock tattoos.

Reversible: No.

This is one of the more versatile rewards, letting you tailor your build defensively (resistances) or Path of Exile 2 Currency for sale offensively (stats).